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Kalident
Biomimetic Hydroxyapatite for Tooth Remineralization
Kalident is an innovative dental-grade Hydroxyapatite developed to mimic the mineral composition, morphology and reactivity of natural tooth enamel, supporting enamel repair, dentin protection and oral health maintenance.
- Applications:Sensitive teeth toothpaste, gels, mouthwash, oral hygiene products
- Main features:supporting enamel repair, dentin protection and oral health maintenance.

Innovation points:
- Biomimetic Hydroxyapatite active ingredient
- Supports enamel remineralization
- Helps occlude exposed dentinal tubules
- Reduces dentin hypersensitivity
- Promotes oral microbiota-friendly formulations
- Suitable for toothpaste, gels and mouthwash applications
What is Kalident Biomimetic Hydroxyapatite?
Kalident is a biomimetic Hydroxyapatite developed by Kalichem to replicate the mineral characteristics of human dental enamel. Hydroxyapatite naturally represents around 97% of tooth enamel and 70% of dentin, making it a highly biocompatible mineral for oral care applications.

How Does Biomimetic Hydroxyapatite Work?
Biomimetic Hydroxyapatite works through a dual mechanism:
- Enamel surface adhesion
The particles integrate with the tooth surface, filling microscopic defects and increasing the mineral reservoir available for enamel repair.
- Calcium and phosphate ion exchange
The pH-dependent dissolution process releases mineral ions into saliva, supporting the physiological remineralization process.
| Benefit | Mechanism |
|
Enamel remineralization |
Mineral deposition and calcium/phosphate release |
|
Plaque reduction |
Oral surface mineral interaction |
|
Microhardness improvement |
Increased enamel resistance |
|
Anti-sensitivity action |
Dentinal tubule occlusion |
|
Tooth surface protection |
Biomimetic mineral coating |
|
Whitening support |
Optical improvement and surface smoothing |
Clinical Evidence:
Dentin Tubule Occlusion
After 5 days of treatment with Kalident® Biomimetic Hydroxyapatite, dentin tubule opening area was reduced by 93%, demonstrating effective tubule occlusion and protection against hypersensitivity.
Whitening Effect
Clinical evaluations showed visible whitening and brightening effects after repeated use of formulations containing Biomimetic Hydroxyapatite.
Anti-Hypersensitivity Effect
80% of panelists reported a high reduction in tooth hypersensitivity after treatment with Biomimetic HAP formulations.
How does Hydroxyapatite help teeth?
Hydroxyapatite is the natural mineral component of tooth enamel. Biomimetic HAP helps restore mineral balance by providing calcium and phosphate ions and integrating with enamel surfaces.
Is Kalident suitable for toothpaste formulations?
Yes. Kalident is designed for toothpaste, gels and opaque mouthwash formulations.
Can Hydroxyapatite reduce tooth sensitivity?
Yes. Biomimetic Hydroxyapatite helps reduce sensitivity by occluding exposed dentinal tubules.
Read now our technical article about Kalident
Ideal for:
- Toothpaste & Mouthwash formulations
- Baby oral care
- Clean beauty oral formulations
- Professional oral treatments
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