Deohap Dry: The Next-Generation Aluminium-Free Solution for Sweat and Odour Control

Kalichem’s Breakthrough: Introducing Deohap Dry

To address these limitations, Kalichem developed Deohap Dry, a biomimetic hydroxyapatite-based complex (HAP complex, INCI: Calcium/Magnesium/Zinc Hydroxyapatite, clay minerals, zinc PCA).

This patented ingredient offers a gentle, effective, and aluminium-free alternative for next-generation deodorant and anti-sweat formulations.

Core Benefits of Deohap Dry:

• Adsorption of odours and sweat

• Deodorizing and bacteriostatic action

• Microbiota balance and skin homeostasis

• Excellent formulation versatility for sprays, sticks, roll-ons, creams, and anhydrous systems

How Biomimetic Hydroxyapatite Works

The biomimetic hydroxyapatite used in Deohap Dry mimics the natural mineral found in human tissues.

Its porous structure and high hydration capacity enable it to effectively adsorb sweat molecules, while its electrophilic properties—enhanced by zinc and magnesium substitution—trap volatile compounds like ammonia and hydrogen sulfide, the primary culprits behind body odour.

📊 Figure 1 demonstrates that the HAP complex maintains its adsorption ability longer than traditional materials such as zeolite and magnesium hydroxide, ensuring continuous odour control even under high perspiration conditions.

Overcoming Formulation Challenges

Creating effective and consumer-pleasant deodorants requires balancing efficacy, stability, and skin safety across various formats—sprays, sticks, roll-ons, and creams.

Conventional actives often fail due to:

• pH instability or incompatibility with emulsifiers

• Sensory issues such as stickiness or visible residue

• Irritation risks when used at higher concentrations

Thanks to its non-irritating, pH-neutral, and invisible texture, Deohap Dry performs consistently across formulations. It’s available in pure powder or 30% aqueous suspension, ensuring easy incorporation into all cosmetic systems.

Efficacy Confirmed by In Vitro and In Vivo Tests

In Vitro Results: Odour Adsorption

Kalichem evaluated the HAP complex through advanced gaseous and liquid experimental models.

Results show superior ammonia, lactate, and urea adsorption compared to zeolite and magnesium salts (📊 Figure 2).

This confirms Deohap Dry’s strong odour-trapping performance and its ability to maintain freshness over time.

In Vivo Results: Sweat Reduction

A clinical gravimetric study conducted on 16 volunteers demonstrated that a deodorant containing 7% Deohap Dry reduced sweat by 35.5% after 24 hours and 30.5% after 48 hours, compared to placebo (📊 Figure 3).

These results meet FDA efficacy criteria for sweat control and confirm the long-lasting deodorizing performance of Deohap Dry.

Formulation Versatility: Multiple Application Systems

Deohap Dry has proven compatibility across multiple product formats:

• Roll-on Deodorant (O/W hyperfluid emulsion)

• Aerosol Spray

• Oily Stick

• Spray Emulsion

• Oily Paste

Each formulation (see Tables 1–5 in the study) demonstrates excellent stability, sensorial performance, and odour reduction, confirming Deohap Dry’s adaptability for both water-based and anhydrous systems.

A New Standard for Skin-Friendly Deodorants

Deohap Dry sets a new benchmark in biotech personal care by combining science, sustainability, and sensory excellence.

It provides:

• Effective sweat and odour control

• No aluminium salts or aggressive chemicals

• Microbiota-friendly balance

• Safe, non-irritating performance

• Sustainable innovation aligned with clean beauty trends

Conclusion

With its biomimetic hydroxyapatite core and proven clinical efficacy, Deohap Dry represents the future of sweat and odour control.

It redefines what a modern deodorant ingredient can achieve—combining biotechnology, dermo-compatibility, and eco-responsibility to meet the evolving needs of conscious consumers.